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CIO WM Global Investment Office
document TEXT-001-HOUSE_OVERSIGHT_025247.txt Oct 25, 2012 House Oversight Committee — Epstein Estate Records (Nov 2025)

CIO WM Global Investment Office CIO monthly video www.ubs.com/cio-video For smartphone users: scan the code with an app like "scan" UBS CIO Monthly Extended November 2012 Published 25 October 2012 This report has been prepared by UBS AG. Please see important disclaimers and disc...

Re: FDA Approved a Potent and Pricey Cholesterol lowering drug today
email TEXT-001-HOUSE_OVERSIGHT_026362.txt Jul 24, 2015 House Oversight Committee — Epstein Estate Records (Nov 2025)

From: jeffrey E. [[email protected]] Sent: 7/24/2015 8:47:39 PM To: Sultan Bin Sulayem Subject: Re: FDA Approved a Potent and Pricey Cholesterol lowering drug today yes, it requires a shot, its not a pill and so far no long term effects known On Fri, Jul 24, 2015 at 4:37 PM,...

Fwd: FDA Approved a Potent and Pricey Cholesterol lowering drug today
email TEXT-001-HOUSE_OVERSIGHT_025888.txt Jul 24, 2015 House Oversight Committee — Epstein Estate Records (Nov 2025)

From: Sultan Bin Sulayem Sent: 7/24/2015 8:37:24 PM To: Jeffrey Epstein [[email protected]] Subject: Fwd: FDA Approved a Potent and Pricey Cholesterol lowering drug today Importance: High Have you heard of this colestrol Jul 24, 2015 @ 3:23 PM 1,169 views The FDA Approves A P...

New Leaf Ventures III, L.P. (““NLV-II” or the “Fund”) is being formed by New Leaf Venture
document IMAGES-007-HOUSE_OVERSIGHT_024012.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

I. EXECUTIVE SUMMARY FUND OVERVIEW New Leaf Ventures III, L.P. (““NLV-II” or the “Fund”) is being formed by New Leaf Venture Partners, L.L.C. (“New Leaf” or the “Management Company”), an established and proven leader in health care technology investing. NLV-III will be the seve...

Top 10 US Ideas Quarterly
document TEXT-001-HOUSE_OVERSIGHT_014622.txt Jan 3, 2017 House Oversight Committee — Epstein Estate Records (Nov 2025)

Top 10 US Ideas Quarterly Q1 Top 10 Ideas Strategy Equity | 03 January 2017 Corrected Top 10 US Ideas – 1Q17 The backdrop for risk assets has changed dramatically over the past year. As Michael Hartnett pointed out, 2016 saw global interest rates fall to 5,000-year lows and the...

Methodology Used to Calculate Net Returns Numbers for Sprout Healthcare Technology
document IMAGES-007-HOUSE_OVERSIGHT_024106.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

Methodology Used to Calculate Net Returns Numbers for Sprout Healthcare Technology Portfolios Estimated net returns numbers for the managed healthcare portfolio of the Sprout funds are based on New Leaf’s calculations of synthetic net returns. The synthetic net returns for the h...

There may be significant delays in obtaining reimbursement for newly approved drugs, and
document IMAGES-007-HOUSE_OVERSIGHT_024071.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

There may be significant delays in obtaining reimbursement for newly approved drugs, and coverage may be more limited than the purposes for which the drug is approved by the FDA or similar regulatory authorities outside the United States. Moreover, eligibility for reimbursement d...

40-Year USA Inc. Data Points and Trends
document IMAGES-006-HOUSE_OVERSIGHT_020865.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

40-Year USA Inc. Data Points and Trends “65-05 1965 2005 Change National’ Healthcare Spending as % of GDP 6% > 16% 167% Federal? Healthcare Spending as % of GDP 1 > 5 o Out-of-Pocket Healthcare Spending as % of GDP 3 > 2 - % of Adult Population Considered Obese 13 > 32 146 % of...

Restructure Medicare & Medicaid: Economic Factors —
document IMAGES-006-HOUSE_OVERSIGHT_020989.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

Restructure Medicare & Medicaid: Economic Factors — Employer and Government Funding System Separates Consumers from True Costs of Healthcare e When one doesn’t pay directly and gets an expensive good / service for free (or well below cost), one tends to consume more - it’s basi...

Restructure Medicare & Medicaid: Economic Factors—
document IMAGES-006-HOUSE_OVERSIGHT_020988.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

Restructure Medicare & Medicaid: Economic Factors— Rise in Usage of “Open Access” Healthcare Plans Makes It Harder to Control Patient Choices...Subsequently, Cost of Care Increases Societal demand for less restrictive health insurance has driven a gradual switch to open access...

EvENING OF AuGusT 22, 2012 1:30 p.m. the Third Place: Healthcare Everywhere
document IMAGES-004-HOUSE_OVERSIGHT_017525.txt Aug 22, 2012 House Oversight Committee — Epstein Estate Records (Nov 2025)

Program EvENING OF AuGusT 22, 2012 1:30 p.m. the Third Place: Healthcare Everywhere HoTeitt KuncG Cari_ BANQUET Patrick Flochel, Global Pharmaceutical Leader, Ernst & Young 6:00 p.m. Welcoming Reception Special Recognition to 1:45 p.m. The Asian Diabetes Etidemit Dr. Laurent Lek...

play a critical role in enabling the necessary structural changes to the healthcare system. The
document IMAGES-007-HOUSE_OVERSIGHT_024019.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

play a critical role in enabling the necessary structural changes to the healthcare system. The HITECH Act created a $25.9 billion!? Federal Government funded catalyst for the adoption of information technology in healthcare in the U.S., and this is stimulating significant invest...

New Leaf team five years ago and has made significant contributions to the NLV-II portfolio
document IMAGES-007-HOUSE_OVERSIGHT_024013.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

New Leaf team five years ago and has made significant contributions to the NLV-II portfolio. Jim Niedel MD PhD has worked with the team continuously for over twelve years and will continue to be a senior member of the NLV investment team for NLV-III, but will change his status to...

generally considered to be representative of U.S. stock market activity. The NASDAQ
document IMAGES-007-HOUSE_OVERSIGHT_024109.txt Mar 31, 2014 House Oversight Committee — Epstein Estate Records (Nov 2025)

QO iw} tH Les a generally considered to be representative of U.S. stock market activity. The NASDAQ Composite Index measures all NASDAQ domestic and non-U.S. based common stocks listed on the NASDAQ Stock Market. The NASDAQ Biotechnology Index includes securities of NASDAQ-l...

For the last several decades the healthcare venture capital industry has been the predominant
document IMAGES-007-HOUSE_OVERSIGHT_024040.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

CONTRACTION IN HEALTHCARE VENTURE CAPITAL INDUSTRY & CAPITAL MARKET DYNAMICS MORE BROADLY CREATE OPPORTUNITY IN DEVELOPMENT STAGE AND EARLY COMMERCIAL STAGE COMPANIES For the last several decades the healthcare venture capital industry has been the predominant source of early an...