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The Fund Managers have been an active investor in the medical device sector across the New
document IMAGES-007-HOUSE_OVERSIGHT_024034.txt Mar 31, 2014 House Oversight Committee — Epstein Estate Records (Nov 2025)

MEDICAL DEVICES RETURNS SUMMARY: The Fund Managers have been an active investor in the medical device sector across the New Leaf and Sprout Funds. Combined, the Fund Managers have invested $371 million in 29 medical device companies, and have gross realizations of $394 million a...

This Memorandum has been prepared for private information purposes only and it may not be used for,
document IMAGES-007-HOUSE_OVERSIGHT_024113.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

This Memorandum has been prepared for private information purposes only and it may not be used for, and shall not be deemed, a public offering of interests in the Fund. This Memorandum is strictly for private use by its holder and may not be passed on to third parties or otherwis...

Regulatory Changes
document IMAGES-007-HOUSE_OVERSIGHT_024082.txt Jun 22, 2011 House Oversight Committee — Epstein Estate Records (Nov 2025)

Regulatory Changes On June 22, 2011, to implement provisions of Title IV of the Dodd-Frank Wall Street Reform and Consumer Protection Act, the U.S. Securities and Exchange Commission (the “SEC”) adopted final rules implementing new exemptions from the registration requirements o...

Portfolio Company Leverage
document IMAGES-007-HOUSE_OVERSIGHT_024076.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

Portfolio Company Leverage To the extent that any investment is made in a portfolio company with a leveraged capital structure, such investment will be subject to increased exposure to adverse economic factors such as a significant rise in interest rates, a severe downturn in th...

outside the Fund, by requiring some or all of the Limited
document IMAGES-007-HOUSE_OVERSIGHT_024065.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

outside the Fund, by requiring some or all of the Limited Partners to make such investment through a limited liability entity that will invest on a parallel basis with, or in lieu of, the Fund, as the case may be. Successor Fund: Without the prior written consent of the Advisory...

Proskauer Rose LLP (“Proskauer Rose”) acts as counsel to the Fund, the General Partner and
document IMAGES-007-HOUSE_OVERSIGHT_024099.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

XII. ADDITIONAL INFORMATION Legal Counsel Proskauer Rose LLP (“Proskauer Rose”) acts as counsel to the Fund, the General Partner and the Management Company in connection with the organization of the Fund and the offering of Limited Partner Interests therein. Proskauer Rose also...

prescription drug costs during the temporary “gap” from Medicare coverage until their
document IMAGES-007-HOUSE_OVERSIGHT_024072.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

prescription drug costs during the temporary “gap” from Medicare coverage until their prescription drug costs reach the threshold for catastrophic coverage by Medicare), (iii) an approval process for generic biologics and granting exclusive marketing rights to original manufactur...

COMPLIANCE DEADLINES — Second Quarter 2017
document IMAGES-005-HOUSE_OVERSIGHT_019861.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

COMPLIANCE DEADLINES — Second Quarter 2017 There are many regulatory filings and compliance forms that investment managers need to complete throughout the year. Below is a list of some of the key com- pliance dates for the second quarter of 2017. Please note that this is general...

New Leaf’s investment strategy is differentiated in the venture capital industry in terms of its
document IMAGES-007-HOUSE_OVERSIGHT_024042.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

V. NEW LEAF VENTURE PARTNERS INVESTMENT STRATEGY New Leaf’s investment strategy is differentiated in the venture capital industry in terms of its sector focus, specific approaches within each sector, and the depth of experience and long-term track record that supports each eleme...

charged to a Partner without regard to whether the General Partner made either of the elections
document IMAGES-007-HOUSE_OVERSIGHT_024086.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

charged to a Partner without regard to whether the General Partner made either of the elections described above on behalf of the Fund. Furthermore, each Partner will be required to provide the Fund with any information necessary to allow the Fund to comply with its obligations to...

New Leaf team five years ago and has made significant contributions to the NLV-II portfolio
document IMAGES-007-HOUSE_OVERSIGHT_024013.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

New Leaf team five years ago and has made significant contributions to the NLV-II portfolio. Jim Niedel MD PhD has worked with the team continuously for over twelve years and will continue to be a senior member of the NLV investment team for NLV-III, but will change his status to...

Power, Fortune and Survival in the Age of Networks
document TEXT-001-HOUSE_OVERSIGHT_018232.txt House Oversight Committee — Epstein Estate Records (Nov 2025)

…il of a single adventurer like Marco Polo, carried promises of prosperity (and intimations of violence) as they spread. Baron Antoin-Henry Jomini, Napoleon’s inspired tactical accomplice, was onto something when he remarked that it was the interior, networked lines of communicati...

returns, and might be liable for U.S. tax in excess of the amount collected by withholding
document IMAGES-007-HOUSE_OVERSIGHT_024092.txt Jul 1, 2014 House Oversight Committee — Epstein Estate Records (Nov 2025)

returns, and might be liable for U.S. tax in excess of the amount collected by withholding. Similarly, Non-U.S. Partners could become subject to U.S. federal income tax and tax return filing obligations, as a result of transfers of their Limited Partner Interests at a time when t...