The Fund Managers have been an active investor in the medical device sector across the New

MEDICAL DEVICES RETURNS SUMMARY: The Fund Managers have been an active investor in the medical device sector across the New Leaf and Sprout Funds. Combined, the Fund Managers have invested $371 million in 29 medical device companies, and have gross realizations of $394 million and a 1.82x gross realized Multiple and 9.4% gross realized IRR. Table 3 summarizes the gross realized and unrealized returns from medical device investments in each New Leaf fund and the Sprout Funds: Table 3: Gross Medical Device Performance by Fund Group $ amounts in millions, as of March 31, 2014 Deals Total Cost Total Realized Unrealized Realized Overall Realized Overall New Leaf Ventures II, L.P. (2008) 5 $72.0 $52.5 $1.8 $50.6 0.11x 0.73x N/A 9.2% New Leaf Ventures I, L.P. (2005) 6 $73.3 $146.4 $67.3 $79.2 5.64x 2.00x 58.8% 15.5% All Sprout Funds (1993, 1995, 1998, 2000) 18 $225.2 $328.9 $325.1 $3.7 1.73x 1.46x 8.3% 6.1% Total 29 $370.5 $527.8 $394.2 $133.5 1.82x 1.42x 9.4% 6.6% Please see the endnotes in Appendix 4 for definitions of terms and/or methodology. Note that these gross returns are for portions of each fund, broken out by investment sector subfocus. Management fees, the general partner’s carried interest and other expenses are applied on a fund level and not based on individual investments or a portion of the investment portfolio. For net returns on each fund which would include these items, please see Appendix 2. TOOLS, DIAGNOSTICS, & INFRASTRUCTURE RETURNS SUMMARY: The Fund Managers have made investments in the tools, diagnostics, and infrastructure sector across the New Leaf and Sprout Group funds. The strategy has included predominantly later/commercial stage tools and infrastructure investments and a mix of early/development stage and later/commercial stage diagnostics companies over time. Combined, the Fund Managers have invested in 17 companies, for a total $221 million in cost. The Fund Managers have generated gross realizations of $261 million, for a 1.50x gross realized Multiple and 14.2% gross realized IRR. Table 4 summarizes the gross realized and unrealized returns from tools, diagnostics, and infrastructure investments in each New Leaf fund and the Sprout Funds: Table 4: Gross Tools, Diagnostics, & Infrastructure Performance by Fund Group $ amounts in millions, as of March 31, 2014 Deals Total Cost Total Realized Unrealized Realized Overall Realized Overall New Leaf Ventures II, L.P. (2008) 3 $31.0 $36.1 $0.0 $36.1 0.00x 1.16x N/A 4.8% New Leaf Ventures I, L.P. (2005) 2 $25.7 $1.7 $1.7 $0.0 0.06x 0.06x N/A N/A All Sprout Funds (1993, 1995, 1998, 2000) 12 $164.0 $273.1 $258.8 $14.3 1.88x 1.67x 16.4% 13.9% Total 17 $220.7 $310.9 $260.5 $50.4 1.50x 1.41x 14.2% 11.9% Please see the endnotes in Appendix 4 for definitions of terms and/or methodology. Note that these gross returns are for portions of each fund, broken out by investment sector subfocus. Management fees, the general partner’s carried interest and other expenses are applied on a fund level and not based on individual investments or a portion of the investment portfolio. For net returns on each fund which would include these items, please see Appendix 2. For further detail on prior performance, please refer to the Appendices and endnotes hereto. 23 CONTROL NUMBER 257 - CONFIDENTIAL HOUSE_OVERSIGHT_024034