more likely to get angry and violent in the face of frustration and other emotional challenges, wher
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more likely to get angry and violent in the face of frustration and other emotional challenges, whereas the
high expressing form builds a child that is walled off, immune to the same challenges.
MAOA is crucial not only in long term human development, but also in everyday, ephemeral
social interactions. In a laboratory study, an experimenter offered subjects the opportunity to earn up to
$10 on a vocabulary quiz. Once they finished the quiz, they learned that an anonymous person in another
room either took some of their earnings or left it alone. With this information in hand, the quiz-taker
could either vindictively punish the person by giving them some hot sauce or they could cash out of the
game and recover the money lost. In other words, they could either vindictively burn their opponent or
recover their losses at no cost. In reality, there was no partner in the other room. When subjects with the
low expressing form of MAOA lost most of their earnings, they were far more likely to deliver the hot
sauce than those with the high expressing form; they were also most likely to deliver the highest amount
of the sauce. Like long-term parental abuse, even short-term provocation invoked in a laboratory
environment can cause those with the low expressing form of MAOA to act out and attack.
As with all genes that have different forms, the number of individuals with the low expressing
form of MAOA varies by population, including different ethnic and culturally identified groups.
Caucasian and Hispanic males show some of the lowest frequencies at 34 and 29 % respectively, whereas
Maori, Pacific Islander, and Chinese males show the highest at 56, 61, and 77% respectively. In a study of
over 1000 men, individuals with the low expressing form of MAOA were more likely to be in violent
gangs, and once in gangs, were more likely to use guns and knives than individuals with the high
expressing form. Variation in the frequency of these two forms is interesting as it provides the signature
handiwork of natural selection. When the frequency of one form goes up, the most likely explanation is
that this form benefits the individual carriers. When the frequency goes down, there is a hidden cost. In
light of this teeter-tottering of frequencies, the Maori are of interest. As celebrated by many New
Zealanders today, the Maori were a highly adventurous and warring people. Individuals who took risks
and fiercely defended their resources were heroes. Heroes may have been carriers of the low expressing
form of MAOA. Heroes often leave more offspring, who were also carriers of the low expressing form.
In the Maori environment, selection may well have favored this form of the gene. The important point is
that different environments will favor different frequencies of the two forms of MAOA. This helps
explain both the cause of individual differences and the challenges we face in confronting cultures of
violence that are fueled by nature and nurture.
Many other labs have followed up on Caspi and Moffitt’s long term, developmental study. Most
find the same relationship between the MAOA gene and antisocial behavior. Others add to this account
by showing how different genes and early appearing physiological differences contribute to a highly
aggressive and antisocial starting state. In one study, the German psychologist Alexander Strobel put
Hauser Chapter 4. Wicked in waiting 126
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